Scientists Have Been Able to Reverse Alzheimer«s Disease 0 51

Researchers from the Institute of Bioengineering of Catalonia and the University of Western China have presented a technology that allowed for the reversal of Alzheimer's disease in mice. Unlike traditional drugs, the nanoparticles described in the study published in Signal Transduction and Targeted Therapy (STTT) act as a standalone medication, restoring the function of brain blood vessels and the barrier between blood and nerve tissue.

The scientists found that damage to the vascular system and the disruption of the brain's clearance of toxic proteins, such as amyloid-β, play a key role in the development of dementia. After three injections of nanoparticles, the level of amyloid in the brains of the mice decreased by 50–60 percent in just one hour, and after a few months, the animals fully restored their cognitive functions.

The authors emphasize that the effect is related to the restoration of normal blood vessel function in the brain. This opens up a new approach to the therapy of neurodegenerative diseases, where the key is not the impact on neurons, but the restoration of vascular health and the natural mechanisms of brain clearance.